Susan Hayflick Selected Research

Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)

1/2022	Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism.
1/2020	Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
1/2017	Changes in Red Blood Cell membrane lipid composition: A new perspective into the pathogenesis of PKAN.
3/2013	Mineral deposition on magnetic resonance imaging in chorea-acanthocytosis: a pathogenic link with pantothenate kinase-associated neurodegeneration?
12/2012	Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model.
12/2011	Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
4/2010	Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.

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Susan Hayflick Research Topics

Disease

7	Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease) 01/2022 - 04/2010
4	Neurodegeneration with brain iron accumulation (NBIA) 01/2017 - 12/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2013 - 04/2010
1	Pyruvate Dehydrogenase Complex Deficiency Disease 01/2020
1	Brain Diseases (Brain Disorder) 01/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Cerebral Palsy (Spastic Diplegia) 01/2020
1	3-Methylglutaconic Aciduria 01/2020
1	Deafness (Deaf Mutism) 01/2020
1	Basal Ganglia Diseases (Basal Ganglia Disease) 01/2020
1	succinic semialdehyde dehydrogenase deficiency 01/2020
1	Kearns-Sayre Syndrome 01/2020
1	Kernicterus 01/2020
1	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2020
1	Atypical Rett Syndrome 03/2015
1	Neuroacanthocytosis 03/2013
1	Movement Disorders (Movement Disorder) 01/2013
1	Parkinsonian Disorders (Parkinsonism) 11/2012
1	Neuroaxonal Dystrophies (Neuroaxonal Dystrophy, Late Infantile) 11/2010
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2010

Drug/Important Bio-Agent (IBA)

5	IronIBA 03/2015 - 12/2012
4	Coenzyme A (CoA)IBA 01/2022 - 04/2010
3	pantothenate kinaseIBA 01/2017 - 04/2010
1	Vigabatrin FDA Link 01/2020
1	Thiamine (Aneurin)FDA Link 01/2020
1	MineralsIBA 03/2013
1	Phospholipases A2 (Phospholipase A2)IBA 11/2012
1	TubulinIBA 12/2011
1	Histones (Histone)IBA 12/2011
1	Phospholipases (Phospholipase)IBA 11/2010
1	CalciumIBA 11/2010
1	pantethineIBA 04/2010
1	Proteins (Proteins, Gene)FDA Link 04/2010